Senior Accountant
Genesis Molecular AI • San Diego, California • Full Time • $85,000–$100,000 / year
Posted on Sat, Sep 26, 2026
Company:
Genesis Molecular AI, Inc. is a biotechnology company that invents and deploys breakthrough AI techniques to discover and develop drugs both internally as well as in select partnerships. Genesis is unique in its groundbreaking deep learning technology, its synergy of machine learning with biophysical simulation and its pairing of AI with extensive biotech/pharma expertise. Its team of technology trailblazers and proven drug developers are driving the discovery and development of novel small molecule drugs to treat patients suffering with severe and debilitating diseases.
Summary:
Genesis is hiring an experienced Senior Accountant to join our company in our San Diego, California location. This is an exciting position with the opportunity to play a key role in building and managing the company’s accounting and operations functions. This position reports directly to the Assistant Controller.
Key Responsibilities:
Maintains the general ledger and handles the month, quarter, and year-end close process.
Prepares monthly and quarterly journal entries, including accruals, depreciation, prepaid expense amortization, and other close-related entries;
Reconciles accounts including cash, prepaid accounts, fixed assets, liabilities, equity, etc;
Analyzes account balances and maintains support for the reconciled balances;
Researches variances and proposes resolution;
Maintains the revenue recognition schedules.
Supports all aspects of the accounts payable function.
Reviews purchase invoices for proper general ledger coding and posting dates;
Prepares use tax returns;
Prepares property tax returns.
Participates actively in the annual financial audit process.
Interacts with the auditors on audit requests;
Assists with preparation of schedules and compiling records for the audit.
Assists with the preparation of the annual financial statements and related disclosures
Assists the Assistant Controller and VP of Finance in collecting and providing data for the annual tax returns.
Other Responsibilities
Assists with the annual 401(k) audit;
Responds to investor information requests;
Supports special projects and other duties as assigned.
Qualifications:
Bachelor’s degree in Accounting or related field required;
CPA preferred;
3+ years of progressive accounting experience;
Biotech company experience preferred but not required;
Strong knowledge and understanding of U.S. GAAP;
Exercises strong judgment and integrity;
Strong interpersonal skills and the ability to communicate effectively across a diverse range of departments and levels, including executive management;
Ability to proactively identify accounting issues and take the initiative to solve challenges.
About Genesis Molecular AI
Genesis Molecular AI is pioneering foundation models for molecular AI to unlock a new era of drug design and development. Our generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), integrates AI and physics into industry-leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction. Genesis is backed by premier AI and life science investors, including a16z, NVIDIA, Rock Springs Capital, Menlo Ventures, T. Rowe Price, Fidelity, and Radical Ventures. Genesis has also signed category-leading AI-pharma deals, the most recent of which was a significant expansion with Incyte (see coverage in Forbes and GEN) with a total potential deal value of several billion dollars.
Genesis is headquartered in San Mateo, CA, with a fully integrated laboratory in San Diego. We are proud to be an inclusive workplace and an Equal Opportunity Employer.
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What the data says about this job
- Advertised pay for Senior Accountant in San Diego: a median of $91,250 across 72 priced postings. This posting advertises $85,000 to $100,000, in line with that median. Explore the market
Measured from employers' own postings and public filings. How we measure