Senior Manager, Commercialization FP&A

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

Revolution Medicines is seeking a Senior Manager, Commercialization FP&A to support our growing Global Commercialization organization. The Senior Manager, Commercialization FP&A will be a key operational finance partner across Global Commercial Development, US Commercialization, and Global Medical Affairs teams. This role reports to the Senior Director, Commercialization FP&A and is based out of our headquarters in Redwood City, CA.

• Support Global Commercialization FP&A cadences including annual budget, quarterly forecasting, and long-range planning; partner with functional leaders to align assumptions, timing, and resource needs and utilize FP&A systems (Adaptive) for consolidation and reporting.

• Own and deliver executive-ready management reporting packages (budget vs. actuals, forecast updates, regional/product P&L views as applicable) and clearly communicate key insights, risks, and opportunities.

• Drive monthly variance analysis of actuals vs. budget/forecast; investigate discrepancies, understand key business drivers, and provide actionable recommendations to stakeholders.

• Provide ad hoc analytical support to enable decision-making, including spend tracking, benchmarking, and scenario analysis (e.g., resourcing trade-offs, vendor strategy, and investment prioritization).

• Lead the monthly accounting close process for Global Commercialization OPEX, including preparation of month-end OPEX accrual journal entries and review of open POs, invoices, and service completion status in coordination with Accounting/Procurement and functional operations teams.

• Establish and maintain governance for PO coding and mapping to ensure alignment to business initiatives, accurate initiative-level reporting, and scalable cost management practices.

• Maintain a continuous improvement mindset across processes, systems, and reporting—identifying opportunities to standardize, automate, and strengthen controls as Revolution Medicines scales into a global, fully integrated commercial-stage company.

Required Skills, Experience and Education:

• Bachelor’s degree in Finance, Accounting, or related field.

• 6+ years’ experience in a similar role in biotechnology industry.

• Highly proficient in Excel, PowerPoint and AI automation (Codex, Claude Code).

• Experience working effectively in a demanding environment with minimal direction.

• Strong work ethic and ability to adjust workload based on changing priorities.

• Highest standards of accuracy, precision, and diligence; highly organized.

• Ability to think creatively, highly driven, and initiative-taking.

• Ability to work effectively and collaboratively cross-functionally with demonstrated ability to multi-task, prioritize options, anticipate challenges, and execute corporate goals.

• Strong analytical and advanced excel skills as well as excellent written and verbal communication skills.

Preferred Skills:

• CPA or MBA preferred.

• Demonstrated experience utilizing financial systems and other business intelligence tools; NetSuite, Adaptive Insights (including OfficeConnect), and Coupa experience.

The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and . For additional information, please contact privacy@revmed.com.

Base Pay Salary Range

$164,000 - $205,000 USD

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