VP, Controller

City Therapeutics ‚Ä¢ Cambridge, Massachusetts ‚Ä¢ Full Time ‚Ä¢ $270,000–$325,000 / year

Posted on Wed, Aug 12, 2026

VP Controller

Company Overview

City Therapeutics is biopharmaceutical company leading the future of RNA interference (RNAi)-based medicine. Co-founded by pioneering industry executives and backed by premier investors, we are rapidly expanding our sustainable product engine, which includes our ongoing Phase 1 clinical trial for CITY-FXI (targeting thromboembolic diseases) and multiple programs advancing toward the clinic.

Position Summary

The VP Controller will lead all global accounting operations, financial reporting, and internal controls. This critical leadership role serves as the accounting architect for the company’s potential transition from a private entity to a publicly traded organization. You will build a public-ready accounting team, implement SOX-compliant systems, and oversee the preparation of SEC filings. This position reports directly to the Chief Financial Officer.

Key Responsibilities:

SEC Reporting & Financial Infrastructure

Financial Operations and Internal Controls

Financial Management and Business Partnering

Qualifications

Compensation

The base salary range provided reflects our current estimate of what we anticipate paying for this position. Your actual base salary will be based on several factors, including job-related skills, experience, internal equity, relevant education or training, and market dynamics. In addition, you will be eligible for an annual bonus, equity compensation, and a competitive benefits package. Pay range is $270,000 to $325,000.

Our Working Model: In Person, By Design

At City, we believe that science and culture thrive together, and that happens best in person. Our working model is clear: we work onsite at our Kendall Square offices five days per week.

This choice reflects our belief that great science and cultures run on connection, fairness, and growth.

We also know that life is not always predictable. When individual needs arise, we are flexible and supportive and work together to balance home life with life at City.

We believe diverse teams drive better science. We welcome applicants from all backgrounds and experiences who share our mission to bring transformative RNAi medicines to patients.

City Therapeutics is an Equal Opportunity and Affirmative Action employer. All qualified applicants will receive consideration without regard to race, color, religion, national origin, gender, gender identity or expression, sexual orientation, age, disability, veteran status, or any other characteristic protected by law.

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