Accounting Manager
Assembly Biosciences, Inc. ‚Ä¢ South San Francisco, California ‚Ä¢ Full Time ‚Ä¢ $123,000–$132,250 / year
Posted on Thu, Jul 23, 2026
POSITION SUMMARY
Position Title: Accounting Manager
Reports to: Senior Director, Controller
Status: Regular, Full-time, Exempt
Location: South San Francisco, CA
Summary: We are seeking an experienced Accounting Manager to manage day-to-day accounting activities to ensure compliance with U.S. GAAP, internal policies, SOX Controls and external audit. This role requires hands-on payroll expertise.
This position is based in our South San Francisco, CA, location, with flexibility to work remote, and will periodically be required to be on-site.
Specific responsibilities include, but are not limited to:
- Managing general ledger accounting functions, including, but not limited to: allocations, payroll accounting, fixed assets, accounts payable, accruals and cash.
- Preparing and booking journal entries with a strong understanding of the underlying accounting logic and supporting documentation.
- Owning multi-state payroll accounting and processing in Paylocity, including tax setup and compliance across jurisdictions, payroll journal entries, reconciliations, and troubleshooting.
- Serving as the primary preparer for weekly vendor changes and vendor payment runs, applying strong fraud-prevention judgment to detect and escalate suspicious changes (e.g., bank detail edits, new vendor requests, duplicate payments).
- Managing the employee expense reimbursement program, including administration of the expense reporting system, policy compliance reviews, employee support, and related reconciliations.
- Coordinating Finance-related onboarding and offboarding activities, including system access provisioning, user maintenance, and training for Finance applications and processes.
- Preparing quarterly government census/statistical filings accurately and on time.
- Helping with the 401K, quarterly and year-end financial audit activities.
- Monitoring and analyzing financing accounting data.
- Performing ad hoc analysis and projects as requested.
- Be a trusted business partner and advisor to various stakeholders within Finance and Accounting and across the Company.
- Proactively liaise with external auditors to drive timely closure of PBC requests and auditor inquiries.
This job description outlines the primary duties and responsibilities of the role; however, it is not intended to be all-inclusive. The scope of responsibilities may be modified, expanded, or adjusted at the discretion of the organization to meet evolving business needs.
Qualifications Include:
- Bachelor’s degree in Accounting or Finance
- 5+ years of relevant accounting experience, including direct, hands-on experience with multi-state payroll
- Demonstrated proficiency payroll processing, tax filings, and reporting — able to work independently in the system without heavy vendor support
- Strong technical accounting skills, including the ability to independently prepare and book journal entries and reconcile complex accounts
- Experience with accounts payable/vendor management controls, with a clear understanding of fraud risk indicators in vendor setup and payment processes
- Excellent verbal and written communication abilities across all levels of an organization
- Ability to prioritize workloads, tasks, meet deadlines and respond to changing priorities in a hyper-growth environment
- Experience with Oracle Fusion, Paylocity, Fidelity and Concur a plus
- Proficiency in Excel and PowerPoint required
- Previous experience in Life Sciences or Biopharma a plus
Pay Range: $123,000 - $132,250 annualized
The stated pay range for this position reflects the San Francisco Bay Area job market. Assembly Bio establishes pay ranges based on geographic work locations. Additional factors such as academic credentials and relevant experience will influence the actual salary offered.
About Assembly Bio
Assembly Bio (NASDAQ: ASMB) is an ambitious biopharmaceutical company dedicated to the development of innovative small-molecule therapeutics designed to change the path of serious viral diseases and improve the lives of patients worldwide. Led by an accomplished team of leaders in virologic drug development, Assembly Bio is committed to improving outcomes for patients struggling with the serious, chronic impacts of herpesvirus, hepatitis B virus (HBV) and hepatitis delta virus (HDV) infections.
We pride ourselves on creating a culture and work environment that is scientifically driven, ambitious, and collaborative. We encourage diversity of thought that leads to great innovation and are looking to add great people to our dynamic team who are driven to transform the lives of patients. We set our sights high—and pursue our goals with determination. Our unique organization stands ready to welcome talented, motivated individuals, who share our ambitions.
As an equal opportunity employer, we are committed to diversity and inclusion and will
not tolerate discrimination and harassment of any kind. All employment decisions are based on business needs, job requirements and individual qualifications, without regard to race, color, religion or belief, national, social or ethnic origin, sex (including pregnancy), age, physical, mental or sensory disability, HIV status, sexual orientation, gender identity and/or expression, marital, civil union or domestic partnership status, past or present military service, family medical history or genetic information, family or parental status, or any other status protected by the laws or regulations in the locations where we operate.
Information for Recruitment Agencies
Assembly Bio does not accept from recruiters/agencies any unsolicited resumes, or any candidate information including blinded resumes and will not be responsible for any fees related to resumes or candidate information that is unsolicited. Please do not contact hiring managers or Assembly Bio employees directly with any information related to a resume or a candidate. We handle all recruiting through our internal Human Resources team, and we will reach out to you directly should we wish to engage in a search. Your willingness to comply with this will significantly impact any decision we may make about doing business with you.
More live accounting_manager roles
- Manager, Accounting at Atrium Therapeutics — San Diego, California, United States
- Manager, Accounting Advisory - Behavioral Health Industry at Wipfli — Milwaukee, Wisconsin, United States
- Accounting Manager at Bergstrom Auto — Neenah, Wisconsin, United States
- Manager, Accounting Advisory - Behavioral Health Industry at Wipfli — Naperville, Illinois, United States
- Accounting Manager at Morningstar, Inc. — Chicago, Illinois, United States
- Outsourced Accounting Manager - Life Science at Citrin Cooperman Advisors — Braintree, Massachusetts, United States
- Accounting Manager at Clarity Care — Oshkosh, Wisconsin, United States
- Accounting Manager - On Site Only at Blue Streak 1 — Miami, Florida, United States
- Staff Accountant / Accounting Manager Growth Path at Hulett Brand — West Palm Beach, Florida, United States
- Accounting Manager at Bandit Running — Brooklyn, New York, United States
- Part-Time Faculty: ACC 252: Introduction to Managerial Accounting (Fall 2026) at Syracuse — Syracuse, New York, United States
- Manager, Assurance and Accounting at Experienced Career — Edmonton, Alberta, Canada
- Accounting Manager at CSL-Consulting — Burlington, Massachusetts, United States
- Accounting Manager at Tentac Enterprises — Bloomington, Illinois, United States
- Dual Accounting Manager at Azul Hospitality — Napa, California, United States
- Accounting Manager at Los Angeles County Fair Association — Pomona, California, United States
- Accounting Manager at Exponent — St Louis, Missouri, United States
- Accounting Manager at Verismo Therapeutics — Philadelphia, Pennsylvania, United States
- Accounting Manager at WGA — Houston, Texas, United States
- Automotive Accounting Manager at Germain Honda of Beavercreek — Beavercreek, Ohio, United States
- Accounting Manager at Heritage Tractor — Baldwin City, Kansas, United States
- Accounting Manager at Evergreen Residential — Dallas, Texas, United States
- Manager, Finance and Accounting at Compensation Rating & Inspection Bureau — Newark, New Jersey, United States
- Accounting Manager - Management at Woda Cooper — Columbus, Ohio, United States
- Accounting Manager at Mill — San Bruno, California, United States
- Accounting Manager at Police Athletic League — New York, New York, United States
- Dual Accounting Manager at Hotel Centro Sonoma — Napa, California, United States
- Segment Accounting Manager at Insurica — Oklahoma City, Oklahoma, United States
- Manager, Accounting at United Network For Organ Sharing — Richmond, Virginia, United States
- Accounting Manager at Mill Creek Lumber & Supply Company — Tulsa, Oklahoma, United States
- General Ledger Accounting Manager at Globality — Palo Alto, California, United States
- Manager, Accounting at Adobe — Dublin, Ireland
- Manager, Infrastructure Capex Accounting at Anthropic — San Francisco, CA, United States
- Accounting Manager, Program at Njeda — New Jersey, United States
- Fund Accounting Manager at U.S. Bank — Dublin, Ireland
- Accounting Manager at Medica Health Management — Southlake, Texas, United States
- Manager, Accounting Advisory, Behavioral Health Industry at Wipfli — Minneapolis, Minnesota, United States
- Accounting Manager at Arkray Group — Plano, Texas, United States
- Manager, Accounting at Travelers — Hartford, Connecticut, United States
- Accounting Services Manager/CPA | Public Accounting at Dunlapslk Pc — Chalfont, Pennsylvania, United States
- Accounting Manager at Dbm Global — Phoenix, Arizona, United States
- Accounting Manager — Pompano Beach, Florida, United States
- Accounting Manager at Hotel Drover — Fort Worth, Texas, United States
- PMO Manager - Accounting & Finance Services at Baker Tilly — Frisco, Texas, United States
- Accounting Manager at CADY — Alpharetta, Georgia, United States
- Construction Accounting Manager at Evergreen Real Estate Services — Chicago, Illinois, United States
- Accounting Manager at Ehlers — Minneapolis, Minnesota, United States
- Program Manager, Accounting Transformation, Finance & Business Integration at Amazon — Seattle, Washington, United States
- Accounting Manager at Dickerson Bakker (Remote)
- Accounting Manager at Opentech Alliance — Phoenix, Arizona, United States
- Accounting Manager at The Cleveland Electric Laboratories Company — Twinsburg, Ohio, United States
- Accounting Manager at San Diego Rescue Mission — San Diego, California, United States