General Ledger Accountant
Replimune • Woburn, Massachusetts • Full Time
Posted on Sat, Aug 8, 2026
Overview
Replimune’s mission is to revolutionize cancer treatment with therapies designed to activate a powerful and durable full-body anti-tumor response, boldly transforming cancer care because patient’s lives depend on it.
At Replimune, we live by our values:
United: We Collaborate for a Common Goal.
Audacious: We Are Bold.
Dedicated: We Give Our Full Commitment.
Candid: We Are Honest With Each Other.
People are at the center of everything we do, and when it comes to our employees, we make it personal. With a deep sense of purpose, a strong and evolving culture, a competitive and forward-looking total rewards program, everyone at Replimune has a unique opportunity to impact on the lives of patients, caregivers and themselves.
Join us, as we reshape the future.
Summary of Job Description:
Replimune is a fast-paced start-up environment that is constantly evolving. We are looking for a skilled General Ledger Accountant to join our Finance department. The General Ledger Accountant’s responsibilities include preparing entries and monthly account reconciliations for cash, investments, prepaids, PP&E, accrued expenses, and account payable as part of the monthly close. The General Ledger Accountant will also be assisting the team with ad hoc projects and audit requests.
This position is based in our Woburn office and welcomes hybrid work! Local candidates are expected to be on-site a minimum of 2 days per week.
Key Responsibilities
Prepare and record journal entries for Replimune, Inc. and affiliated entities across the general ledger, including investments, prepaids, PP&E, leases, accrued expenses, and accounts payable.
Support the accrual of clinical vendor and principal investigator expenses.
Review daily cash transactions and record cash transactions accurately and timely in Oracle Fusion.
Perform monthly account analyses and FloQast reconciliations and support the entry of FX rates in Oracle.
Review and process credit card expense reports and receipts for policy compliance and ensure appropriate accounting for expense report transactions.
Review, approve and pay out weekly employee expense reports through Concur system
Serve as backup to the Accounts Payable team in AP batch processes, as necessary.
Maintain SOX internal controls documentation over responsible areas.
Assist with preparing schedules for SEC reporting and as support for external audits and reviews, including the PP&E roll forward.
Maintain effective relationships with other departments to ensure effective and efficient cross-functional collaboration
Educational Requirements
A bachelor’s degree in Accounting or Finance.
Experience and Skill Requirement:
Prior relevant experience preferred and solid knowledge of US GAAP.
Bachelor’s degree in accounting preferred.
Proficiency in MS Office, particularly with Excel.
Previous experience with accounting systems preferred; knowledge of Oracle Fusion is a plus.
Prior experience with SAP Concur or FloQast is a plus.
A high degree of accuracy and attention to detail.
Strong analytical and problem-solving skills.
Salary Range
Replimune is committed to fair and equitable compensation practices, and we strive to provide employees with total compensation packages that are market competitive. For this role, the anticipated base pay range is $80,500 $104,000. The exact base pay offered for this role will depend on various factors, including but not limited to the selected candidate’s unique set of qualifications, skills, and experience. Our current organizational needs also play a part in determining your final offer.
At Replimune, base pay is only one part of your total compensation package. The selected candidate will be eligible for an annual performance incentive bonus, new hire equity, and ongoing performance-based equity. Replimune also offers various benefits offerings, including, but not limited to, medical, dental, and vision insurance, 401k match, flexible time off, and a number of paid holidays including year-end shutdown.
About Replimune
Replimune Group, Inc., headquartered in Woburn, MA, was founded in 2015 with the mission to transform cancer treatment by pioneering the development of a novel portfolio of oncolytic immunotherapies. Replimune’s proprietary RPx platform is based on a potent HSV-1 backbone intended to maximize immunogenic cell death and the induction of a systemic anti-tumor immune response. The RPx platform is designed to have a unique dual local and systemic activity consisting of direct selective virus-mediated killing of the tumor resulting in the release of tumor derived antigens and altering of the tumor microenvironment to ignite a strong and durable systemic response. The RPx product candidates are expected to be synergistic with most established and experimental cancer treatment modalities, leading to the versatility to be developed alone or combined with a variety of other treatment options. For more information, please visit www.replimune.com.
We are an Equal Opportunity Employer.
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