Senior Manager FP&A
Monte Rosa Therapeutics • Boston, MA • Full Time
Posted on Tue, Oct 6, 2026
Overview
We are seeking a Senior Manager, FP&A to join our Boston-based Finance team. Reporting to the Director, FP&A, this individual will support and own planning, forecasting, and analytics across a significant portion of the Company's operating expense base, partnering directly with department leaders to translate strategic priorities into credible financial plans.
This is a broad, high-visibility role with exposure to both our scientific organization and our corporate functions. You will be a core contributor to the annual planning cycle, quarterly reforecasts, monthly close, cash and runway analysis, and Board-level reporting. The scope is intentionally wide — we are looking for someone who wants to understand how the whole company works, not just one slice of it.
Responsibilities
Operating plan and forecasting: Own the annual operating plan, quarterly reforecasts and long-range plan for assigned areas.
Driver-based modeling: Build and maintain driver-based models for headcount, personnel costs, external spend, consumables, capital and allocations.
Variance analysis and reporting: Prepare monthly and quarterly reporting packages with budget-versus-actual variance analysis. Include forward-looking commentary on the full-year outlook.
Cash and runway modeling: Contribute to cash forecasting, burn analysis and runway management. Support financing planning, Board materials, budget presentations and external operating expense guidance.
Contract and investment modeling: Build financial models and decision support for CRO/CDMO and vendor contracts, collaborations, capital equipment, software and facilities. Evaluate resource allocation trade-offs across programs, platforms and infrastructure.
Headcount and compensation modeling: Model headcount plans, compensation cycles, recruiting plans and payroll/benefits forecasts with People Experience & Operations.
Month-end close and expense accounting: Work with Accounting on accruals, reclasses and spend validation. Check that expense classification follows policy and external reporting requirements.
Systems, controls and process: Improve FP&A processes, reporting templates and self-service reporting in NetSuite and planning tools. Support internal controls, SOX-readiness and audit requests on budgeting and forecasting.
Qualifications
Education: Bachelor's degree in Finance, Accounting, Economics or a related quantitative field.
Experience: 7–10+ years of progressive FP&A, corporate finance or accounting experience.
Budget and forecast ownership: Demonstrated ownership of multiple full budget and forecast cycles for meaningful cost centers, including direct work with senior non-finance leaders.
Modeling: Advanced Excel and financial modeling skills, able to build a clean, auditable, flexible model from a blank sheet.
Accounting: Strong command of accrual accounting and the month-end close process.
Preferred biotech and systems background: Biotech, pharma or life sciences experience, ideally at a clinical-stage company, with exposure to R&D cost centers. Also hands-on NetSuite and an EPM/planning tool (e.g., Adaptive), plus familiarity with public company reporting (10-Q/10-K, SOX, Board reporting).
AuditFriendly salary estimate
The employer did not post a salary for this role. Based on AuditFriendly's salary intelligence model (comparable live postings, role, seniority, and location), we estimate base pay of $92,000–$162,000 per year (median ~$119,000). This is an AuditFriendly estimate, not an employer-provided figure.
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