Senior Director, Accounting
Uniquity Bio • Malvern, PA • Full Time
Posted on Wed, Sep 23, 2026
Uniquity Bio is a clinical-stage biotechnology company committed to putting science and patients first. We exist to develop transformative new medicines for immune-mediated diseases, and we’re looking for bright-minded professionals driven by a desire to advance science and make a difference for people in need. Our lead asset, solrikitug, is a highly-potent TSLP inhibitor now in Phase 2 clinical trials for asthma, chronic obstructive pulmonary disease (COPD), and eosinophilic esophagitis (EoE) indications.
Join us in building an organization where people and science thrive together. You’ll have the opportunity to make a meaningful impact while working alongside a talented, agile team in an environment where ideas move quickly, colleagues are trusted, and quality remains a cornerstone.
Position Overview
The Senior Director, Accounting is the senior-most accounting leader in the company and owns the accounting close, external audit, technical accounting, and the buildout of the control environment required of a public company. This is a hands-on role for a leader who is comfortable both setting policy and preparing the schedules that support it.
Key Responsibilities
Financial close and reporting
- Own the monthly, quarterly, and annual close, including consolidation, account reconciliations, and the reporting calendar.
- Prepare GAAP financial statements and supporting footnotes for the board, the audit committee, and investors.
- Establish close metrics and drive continuous reduction in cycle time without loss of accuracy.
Clinical and R&D accounting
- Own the clinical trial accrual process in partnership with Clinical Operations, including CRO and site-level cost tracking, enrollment-based estimates, and prepaid and accrued research balances.
- Review vendor contracts, work orders, and change orders for accounting implications and cost recognition.
- Partner with FP&A to reconcile program spend to budget and to explain variances at the study level.
Technical accounting and policy
- Research and document positions on stock-based compensation, equity and preferred stock instruments, leases, revenue and collaboration arrangements, and going concern.
- Maintain the accounting policy manual and the technical memoranda file that supports the audit.
- Serve as the internal authority on new accounting standards and their impact on the company.
Audit and public company readiness
- Manage the annual audit and any interim reviews, serving as primary contact for the external auditors.
- Lead preparation of financial statements suitable for a registration statement, including any required carve-out, predecessor, or comparative periods.
- Design and implement the internal control framework, documentation, and remediation plan necessary to support Section 404 compliance on the applicable timeline.
Operations and team
- Own accounts payable, procurement support, payroll accounting, equity administration, and treasury operations.
- Coordinate income tax provision, compliance, and R&D credit studies with external tax advisors.
- Build and lead the accounting team, and manage outsourced service providers and consultants.
- Own the ERP and related finance systems, including selection, implementation, and process automation.
Qualifications
- Bachelor’s degree in accounting or finance.
- Active CPA.
- Twelve or more years of progressive accounting experience, including public accounting and a controllership or assistant controller role in industry.
- Direct experience with clinical-stage life sciences accounting, including R&D accruals and CRO cost estimation.
- Demonstrated command of US GAAP and SEC reporting requirements.
- Experience building processes and controls in a company without an established accounting infrastructure.
Preferred
- Big Four audit background serving life sciences clients.
- Experience supporting an initial public offering, a reverse merger, or another significant capital markets transaction.
- Experience with a private equity or venture-backed sponsor and its reporting expectations.
- Hands-on ERP implementation experience.
Other
- Comfort operating in a small team where the senior leader also builds the schedule.
- Clear written communication, particularly in technical memoranda and board materials.
- Sound judgment under estimation uncertainty, which is the daily condition of clinical accounting.
- Credibility with auditors, the audit committee, and cross-functional partners in clinical, regulatory, and legal.
Work Environment
At Uniquity Bio, we believe every team member has an impact on the patients we aim to serve. We are a nimble team with a rigorous approach to drug development that requires collaboration and transparency to maximize value, reduce risk, and deliver meaningful, best-in-class products. We are looking for self-starters who enjoy working in a complex, collaborative environment and are motivated to bring critical new medicines to people around the world. We are a small, fast-paced organization with a talented team of in-house employees and external consultants. Candidates must be self-motivated and able to work both independently and collaboratively to achieve success and impact in our dynamic work environment.
This is a U.S.-based position. Team members who live within commuting distance of our Malvern, PA office location are expected to spend time in the office, and remote employees are expected to travel to an office on a regular basis. Specific details for both local and remote staff will be discussed and agreed upon on a case-by-case basis with the employee’s manager. Business travel may be required depending upon the specific needs of the position.
The above job description is not intended to be all-inclusive. Requirements of the position may change from time to time based on business needs.
Uniquity Bio is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. All employment decisions are based on business needs, job requirements, and individual qualifications, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran, or disability status.
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