Manager, Payroll and Benefits

Xeris Pharmaceuticals ‚Ä¢ Chicago, Illinois ‚Ä¢ Full Time ‚Ä¢ $103,500–$165,600 / year

Posted on Tue, Aug 18, 2026

Job Description:

The Manager, Payroll & Benefits is a highly visible and critical role, responsible for the operational oversight of the company’s payroll and employee benefits programs. This role ensures employees are paid accurately and timely, benefit programs are administered effectively, and all payroll and benefits processes comply with applicable federal, state, and local regulations.

The Manager will serve as a key partner to Human Resources, Finance, employees, and external vendors, driving operational excellence, process improvements, and a positive employee experience. This role will also leverage HR technology and data to improve efficiency, reporting, compliance, and decision-making across payroll and benefits.

Payroll Management

Benefits Management

Compliance, Risk and Data Management

Team & Vendor Leadership

Skills and Qualifications

The anticipated hourly wage for this position is $103,500-$165,600

NOTE: This job description is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization.


We are committed to offering competitive compensation. Starting pay is determined based on a variety of factors, including the role, job-related knowledge, skills, experience, education, internal equity, market data, and the location of the role, where applicable.


Xeris Pharmaceuticals, Inc. (the “Company”) is an equal opportunity employer and does not discriminate based on race, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, veteran status, genetics or any other characteristic protected by law. All qualified candidates are given equal opportunity and the Company’s employment selection decisions are based solely on job-related factors. NOTE:  This job description is not intended to be all-inclusive. The employee may be required to perform other related duties as needed to meet the ongoing needs of the Company.

The level of the position will be determined based on the selected candidate’s qualifications and experience. Final determination of the actual base salary offered depends on several factors, including but not limited to the candidate’s skills, experience, education, location, and business needs. Employees are eligible for equity or long-term incentive awards, where applicable.  Field Sales role employees are eligible for a quarterly commission structure. Non-Sales role employees are eligible for an annual bonus. The Company also offers a comprehensive benefits package that includes additional elements such as paid time off benefits, various health, vision, and dental insurance options, 401(k) retirement benefits and more for eligible employees. Details about these and other offerings will be provided at the time a conditional offer of employment is made. Candidates are always welcome to inquire about our compensation and benefits package during the interview process. Individuals hired as temporary employees, interns, and preceptors are not eligible for commissions, bonuses, and/or long-term incentive or equity awards.  Eligibility for other benefits will be based on plan documents.


Accessibility & Reasonable Accommodations

If, because of a medical condition or disability, you require a reasonable accommodation or assistance to complete any part of the application process, please send an e-mail to recruiting@xerispharma.com and identify the type of accommodation or assistance you are requesting. Please include the job requisition number in your message. Please note if your request is not for this stated purpose, you will not receive a response to your email. Do not include any medical or health information in this email.


Xeris participates in E-Verify.  E-Verify Participation Poster

EEO is the Law EEO is the Law

EEO is the Law Supplement EEO is the Law Supplement

Pay Transparency Nondiscrimination Provision Pay Transparency Nondiscrimination Provision

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