Manager, Inventory and Operations Accounting

Vaxcyte • San Carlos, California • Full Time • $145,000–$169,000 / year

Posted on Thu, Oct 15, 2026

Join our Mission to Protect Humankind!

Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.    WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values:   *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered.   *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind.   *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives.   *MODEL EXCELLENCE:  The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.

Summary:

The Manager, Inventory and Operations Accounting role will help manage Vaxcyte’s cost accounting functions, including standard costing, inventory valuation, and manufacturing variance analysis. This role also owns the full manufacturing accrual process for the Manufacturing Accounting Team — maintaining accrual trackers, preparing monthly accrual journal entries, reconciling manufacturing general ledger accounts, and preparing manufacturing flux analysis. The Manager, Inventory and Operations Accounting role partners closely with Supply Chain and FP&A to ensure accurate cost data, drive margin improvement initiatives, and maintain strong internal controls over inventory and cost of goods sold (COGS). The ideal candidate combines strong technical accounting skills with the ability to translate cost data into actionable business insights. 

Essential Functions:

Requirements:

Reports to: Associate Accounting Director, Manufacturing   Location: San Carlos, CA   Work Arrangement (may be adjusted based on business needs, job responsibilities, or changes to company policy):  Hybrid (minimum of 3 days per week onsite)    Compensation: The compensation package will be competitive and includes comprehensive benefits and an equity component.   Salary Range: $145,000 – $169,000 (SF Bay Area). Salary ranges for non-California locations may vary. 

Equal Opportunity

We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.

Recruitment Fraud Notice

Please be aware of fraud or scams from individuals, organizations and/or internet sites claiming to represent Vaxcyte in recruitment activities. Vaxcyte has an established recruitment process for all positions prior to issuing an offer for employment and we will never extend unsolicited employment offers or ask candidates to provide financial or sensitive personal information as part of the application process. All legitimate communication from Vaxcyte will come from an official @vaxcyte.com email address. Qualified and interested candidates should apply to current openings at vaxcyte.com/careers.

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