Procurement and Vendor Operations Senior Manager

Vertex Pharmaceuticals • Boston, Massachusetts • Full Time

Posted on Wed, Jun 17, 2026

Job Description

Position Summary

We are seeking an experienced and detail-oriented Senior Manager to support Procurement Operations and Vendor Management within Vertex's BPO-enabled operating model. Reporting to the Associate Director, the Senior Manager will play a critical role in overseeing BPO-delivered activities, monitoring performance against SLAs, enforcing procurement policy compliance, and driving continuous improvement across outsourced procurement workflows.

This role requires a strong operator with excellent analytical and communication skills, and the ability to collaborate effectively with business stakeholders, Finance, Internal Controls, Category Management, and the external BPO partner.

This role also supports operational execution across Procurement Req-to-PO, Service Desk and Vendor Master Data Management activities delivered through the BPO, serving as an operational nerve center within the retained model.

This role does not own enterprise policy, vendor contracts, or audit accountability, but plays a critical role in surfacing risks and driving operational improvements.

Key Responsibilities

BPO Operations Oversight

Policy & Process Compliance

Escalation & Issue Resolution

Performance Reporting & Analytics

Continuous Improvement & Digitization

Risk & Controls

Team Support & Development

Education and Experience

Skills and Competencies

Key Attributes

Pay Range:

$134,400 - $201,600

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.  From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as: 
1.    Hybrid: work remotely up to two days per week; or select
2.    On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. 

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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